Unlike the inexpensive and common cyanocobalamin form of Vitamin B-12, Methyl B-12 uses methylcobalamin - readily available for your cells to absorb. Cyanocobalamin has to go through the first pass of your liver, where a small amount of methylcobalamin is produced. Then it enters your general (systemic) circulation.
Vitamin B12 (as methylcobalamin) is a water-soluble nutrient in the B vitamin family. It supports a healthy mood and neurological function by supporting methionine synthase, an enzyme with downstream effects on neurotransmitter pathways. Methylcobalamin optimizes the metabolism of homocysteine, an amino acid that increases oxidative stress and cardiovascular and neurodegenerative disease risk when elevated. Methylcobalamin also supports healthy red blood cell production and DNA and RNA synthesis, preserving health at a cellular level.
Because age, low stomach acid, and genetic variation can impair absorption of B complex vitamins, this liposomal formulation is designed to deliver B12 faster and more efficiently.
Methyl B12 is a key, bioactive form of B12 that contributes to both methylation and the synthesis of glutathione.
Another unique feature is Methyl B-12's method of delivery. Sprays are known to be more effective in activating saliva glands than capsules, pills, lozenges or drops. This allows the Vitamin B-12 to enter your bloodstream quickly and efficiently.
Symptoms associated with Vitamin B-12 Deficiency
Abnormal gait, bone loss, chronic fatigue, constipation, very low moods, digestive disorders, dizziness, drowsiness, enlargement of the liver, eye disorders, hallucinations, headaches (including migraines), inflammation of the tongue, irritability, labored breathing, memory loss, moodiness, nervousness, neurological damage, palpitations, low blood hemoglobin, ringing in the ears, and spinal cord degeneration.
The American Heart Association suggests that patients with high levels of homocysteine should be sure to get enough folic acid and vitamins B-6 and B-12 in their diet.
When homocysteine reaches high levels in the body, it can be harmful to the heart. Evidence suggests that high homocysteine levels can cause cardiovascular problems, and is associated with stress and brain disease.
The optimal safe range for homocysteine is under 6 micromoles per liter.
One study revealed that a person who took 2000mcg of oral methylcobalamin per day for four months reduced homocysteine levels from 113.4 micromoles per liter to 8.2 (1).
Methylcobalamin is the only form of B-12 that can directly participate in homocysteine metabolism. (2).
According to Ray Sahelian, M.D., vitamin B-12 plays a major role in red blood cell activity, methylation reactions and immune system regulation.
Evidence indicates methylcobalamin has some metabolic and therapeutic applications not shared by other forms of vitamin B-12.
Government studies revealed that Americans' intake of vitamin B-12 is less than 70 percent of the recommended daily allowance.
B-12 Methylcobalamin Spray more than compensates for that by providing 500 mcg per spray.
Sources
(1) B-12: The Vital Vitamin. Oral B-12 equivalent to B-12 injections. Mitchell, Life Extension Magazine. Aug. 1998
(2) Methylcobalamin and Diabetic Neuropathy. Ide H, Fujiya S, Asanuma Y, Tsuji M, Sakai H, Agishi Y, Clinical Therapy. 1987.